Reactions of alkyl 2-benzylidene-2-polyfluoroacylacetates with N,N-dinucleophiles / Pryadeina MV,Burgart YV,Kodess MI,Saloutin VI,Chupakhin ON // RUSSIAN CHEMICAL BULLETIN. - 2004. - V. 53, l. 6. - P. 1261-1266.

ISSN/EISSN:

1066-5285 / нет данных

Type:

Article

Abstract:

Alkyl 2-benzylidene-2-polyfluoroacylacetates react with urea and thiourea to yield 5-ethoxycarbonyl-4-fluoroalkyl-4-hydroxy-6-phenylhexahydropyrimidin-2-on es and -2-thiones and with guanidine sulfate to form 2-amino-5-ethoxycarbonyl-4-fluoroalkyl-6-phenyl- -1,6-dihydropyrimidines and 3,6-diethoxycarbonyl-2,7-difluoroalkyl-4,5-diphenyl-4,5-dihydro-1H-pyrid o{[}1,2-a]pyrimidines, and they react with phenylhydrazine to afford 4-alkoxycarbonyl-3-fluoroalkyl-3-hydroxy-1,5-diphenylpyrazolidines. Hydrazine hydrate catalyzes the formation of 3,5-diethoxycarbonyl-2,6-difluoroalkyl-2,6-dihydroxy-4-phenyl-tetrahydro pyrans. When treated with anhydrous hydrazine and o-phenylenediamine, these esters cleave to form the products of condensation of fluoroacyl ester and benzaldehyde with diamines.

Author keywords:

alkyl 2-benzylidene-2-polyfluoroacylacetates; dinucleophiles; urea; thiourea; guanidine; hydrazine; phenylhydrazine; o-phenylenediamine

DOI:

10.1023/B:RUCB.0000042284.0394

Web of Science ID:

ISI:000224147800019

Соавторы в МНС:

Другие поля

Поле	Значение
Month	JUN
Publisher	CONSULTANTS BUREAU
Address	233 SPRING ST, NEW YORK, NY 10013 USA
Language	English
Research-Areas	Chemistry
Web-of-Science-Categories	Chemistry, Multidisciplinary
Author-Email	saloutin@ios.uran.ru
ResearcherID-Numbers	Burgart, Yanina/T-8025-2017
ORCID-Numbers	Burgart, Yanina/0000-0001-6061-2410
Number-of-Cited-References	16
Usage-Count-Last-180-days	1
Usage-Count-Since-2013	3
Journal-ISO	Russ. Chem. Bull.
Doc-Delivery-Number	857VR