Nano-sized melphalan and sarcolysine drug delivery systems: synthesis and prospects of application / Krasnov V. P.,Korolyova M. A.,Vodovozova E. L. // RUSSIAN CHEMICAL REVIEWS. - 2013. - V. 82, l. 8. - P. 783-814.

ISSN/EISSN:
0036-021X / 1468-4837
Type:
Review
Abstract:
The results of experimental studies concerned with the development of nano-sized drug delivery systems for the antitumour drugs sarcolysine and melphalan are generalized. The structures and biological activities of nanocarriers in comparison with unmodified drugs are discussed. Particular attention is given to the liposomes containing lipid derivatives of sarcolysine and melphalan in the lipid bilayer. The bibliography includes 196 references.
Author keywords:
HP-BETA-CD; POLYMER-BOUND DRUGS; MULTIPLE-MYELOMA; ANTITUMOR-ACTIVITY; MONOCLONAL-ANTIBODIES; CANCER-CHEMOTHERAPY; IN-VITRO; PHARMACEUTICAL APPLICATIONS; CLINICAL-PHARMACOLOGY; APO-NEOCARZINOSTATIN
DOI:
10.1070/RC2013v082n08ABEH00435
Web of Science ID:
ISI:000325074500006
Соавторы в МНС:
Другие поля
Поле Значение
Publisher TURPION LTD
Address C/O TURPION LTD, IOP PUBLISHING, TEMPLE CIRCUS, TEMPLE WAY, BRISTOL BS1 6HG, ENGLAND
Language English
EISSN 1468-4837
Keywords-Plus HP-BETA-CD; POLYMER-BOUND DRUGS; MULTIPLE-MYELOMA; ANTITUMOR-ACTIVITY; MONOCLONAL-ANTIBODIES; CANCER-CHEMOTHERAPY; IN-VITRO; PHARMACEUTICAL APPLICATIONS; CLINICAL-PHARMACOLOGY; APO-NEOCARZINOSTATIN
Research-Areas Chemistry
Web-of-Science-Categories Chemistry, Multidisciplinary
Author-Email ca@ios.uran.ru kormorona@yandex.ru elvod@lipids.ibch.ru
Funding-Acknowledgement Ural Branch of the RAS {[}12-P-234-2003, 12-P-3-1030]; State Programme for the Support of Leading Scientific Schools {[}NSh 5505.2012.3]; Ministry of Education and Science of Russian Federation {[}8098]
Funding-Text This review was prepared with financial support of the Ural Branch of the RAS (Projects 12-P-234-2003 and 12-P-3-1030), the State Programme for the Support of Leading Scientific Schools (Project NSh 5505.2012.3) and the Ministry of Education and Science of Russian Federa tion (Grant No. 8098).
Number-of-Cited-References 196
Usage-Count-Last-180-days 1
Usage-Count-Since-2013 8
Journal-ISO Russ. Chem. Rev.
Doc-Delivery-Number 226YV