Kinetic resolution of (+/-)-2,3-dihydro-3-methyl-4H-1,4-benzoxazine, (+/-)-2-methyl-1,2,3,4-tetrahydroquinoline and (+/-)-2-methylindoline using N-tosyl-(S)-prolyl chloride / Krasnov VP,Levit GL,Bukrina IM,Andreeva IN,Sadretdinova LS,Korolyova MA,Kodess MI,Charushin VN,Chupakhin ON // TETRAHEDRON-ASYMMETRY. - 2003. - V. 14, l. 14. - P. 1985-1988.

ISSN/EISSN:

0957-4166 / нет данных

Type:

Article

Abstract:

Acylation of racemic 2,3-dihydro-3-methyl-4H-1,4-benzoxazine, 2-methyl-1,2,3,4-tetrahydroquinoline and 2-methylindoline with N-tosyl-(S)-prolyl chloride resulted in their kinetic resolution with the predominant formation of (R,S)-diastereoisomeric amides. des being 80, 66 and 38\%, respectively. Recrystallisation of the amides followed by acid hydrolysis gave individual (R)-enantiomers of heterocyclic amines. (C) 2003 Elsevier Science Ltd. All rights reserved.

Author keywords:

ACIDS; PEPTIDES

DOI:

10.1016/S0957-4166(03)00321-5

Web of Science ID:

ISI:000184259500007

Соавторы в МНС:

Другие поля

Поле	Значение
Month	JUL 18
Publisher	PERGAMON-ELSEVIER SCIENCE LTD
Address	THE BOULEVARD, LANGFORD LANE, KIDLINGTON, OXFORD OX5 1GB, ENGLAND
Language	English
Keywords-Plus	ACIDS; PEPTIDES
Research-Areas	Chemistry
Web-of-Science-Categories	Chemistry, Inorganic \& Nuclear; Chemistry, Organic; Chemistry, Physical
Author-Email	ca@ios.uran.ru
Number-of-Cited-References	9
Usage-Count-Since-2013	3
Journal-ISO	Tetrahedron: Asymmetry
Doc-Delivery-Number	703BE