NUCLEOPHILIC-SUBSTITUTION OF HALOGEN IN 4-HALOGENATED DERIVATIVES OF GLUTAMIC-ACID .2. STRUCTURAL EFFECTS OF ARYLAMINE AS NUCLEOPHILE / KRASNOV VP,KOROLEVA MA,EVSTIGNEEVA NG,NIZOVA IA // RUSSIAN CHEMICAL BULLETIN. - 1995. - V. 44, l. 4. - P. 635-638.

ISSN/EISSN:

1066-5285 / нет данных

Type:

Article

Abstract:

Kinetics of nucleophilic substitution of halogen in diastereomeric dimethyl 4-bromo- and 4-iodoglutamates with ortho-, meta-, and para-substituted anilines was studied by HPLC. The threo-diastereomers of the halogenated derivatives react 3-5 times faster than the erythro ones. The structure of the transition state is discussed.

Author keywords:

GLUTAMIC ACID; DIASTEREOSELECTIVITY; NUCLEOPHILIC SUBSTITUTION; RATE CONSTANT; ARYLAMINE

DOI:

10.1007/BF00698493

Web of Science ID:

ISI:A1995RR52700010

Соавторы в МНС:

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Другие поля

Поле	Значение
Month	APR
Publisher	PLENUM PUBL CORP
Address	CONSULTANTS BUREAU 233 SPRING ST, NEW YORK, NY 10013
Language	English
Research-Areas	Chemistry
Web-of-Science-Categories	Chemistry, Multidisciplinary
Number-of-Cited-References	10
Journal-ISO	Russ. Chem. Bull.
Doc-Delivery-Number	RR527