HYDROLYSIS OF FLUOROALKYL-CONTAINING BETA-AMINOVINYL KETONES / BAZHENOVA LN,FILYAKOVA VI,KIRICHENKO VE,PASHKEVICH KI // BULLETIN OF THE ACADEMY OF SCIENCES OF THE USSR DIVISION OF CHEMICAL SCIENCE. - 1991. - V. 40, l. 3, 2. - P. 581-585.

ISSN/EISSN:

0568-5230 / нет данных

Type:

Article

Abstract:

The kinetics of hydrolysis of fluoroalkyl-containing beta-aminovinyl ketones R1C(O)CHC(NHR3)R2, in which the substituents CF3 and HCF2CF2 are in the ketone (R1) or enamine parts of the molecule (R2), was studied. In acid (pH < 5) and alkaline (pH > 10) media, they hydrolyze with the formation of the corresponding amines and beta-diketones. In an alkaline medium, the beta-diketones undergo cleavage to fluorinated acids and methyl ketones. The rate constants of hydrolysis in an acid medium change within a range of four orders, depending on the nature of the substituents. The presence of a fluoroalkyl group at the enamine reaction center increases the hydrolysis rate. In an alkaline medium, the rate constants vary within one order.

Author keywords:

нет данных

DOI:

10.1007/BF00957999

Web of Science ID:

ISI:A1991GM58500005

Соавторы в МНС:

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Другие поля

Поле	Значение
Month	MAR
Publisher	PLENUM PUBL CORP
Address	CONSULTANTS BUREAU 233 SPRING ST, NEW YORK, NY 10013
Language	English
Research-Areas	Chemistry
Web-of-Science-Categories	Chemistry, Multidisciplinary
Number-of-Cited-References	15
Usage-Count-Since-2013	1
Doc-Delivery-Number	GM585