Nonstabilized azomethine ylides as reagents for alkylaminomethylation of aromatic ketones via 5-aryloxazolidines / Moshkin Vladimir S.,Buev Evgeny M.,Sosnovskikh Vyacheslav Y. // TETRAHEDRON LETTERS. - 2015. - V. 56, l. 38. - P. 5278-5281.

ISSN/EISSN:

0040-4039 / нет данных

Type:

Article

Abstract:

Aromatic ketones were found to react smoothly with nonstabilized azomethine ylides, generated in situ from sarcosine/formaldehyde or N-(methoxymethyl)-N-(trimethylsilylmethyl)benzylamine, to give 5-aryloxazolidines which were converted into 2-alkylaminoethanols in moderate to good yields by heating in n-butanol with hydrochloric acid. (C) 2015 Elsevier Ltd. All rights reserved.

Author keywords:

Carbonyl compounds; Nonstabilized azomethine ylides; {[}3+2] Cycloaddition; 5-Aryloxazolidines; 2-Amino-1-arylethanols ONE-POT SYNTHESIS; 1,3-DIPOLAR CYCLOADDITION; CACTUS ALKALOIDS; ALCOHOLS; DECARBOXYLATION; DERIVATIVES; ALDEHYDES; SARCOSINE

DOI:

10.1016/j.tetlet.2015.07.068

Web of Science ID:

ISI:000360510700005

Соавторы в МНС:

Другие поля

Поле	Значение
Month	SEP 16
Publisher	PERGAMON-ELSEVIER SCIENCE LTD
Address	THE BOULEVARD, LANGFORD LANE, KIDLINGTON, OXFORD OX5 1GB, ENGLAND
Language	English
Keywords-Plus	ONE-POT SYNTHESIS; 1,3-DIPOLAR CYCLOADDITION; CACTUS ALKALOIDS; ALCOHOLS; DECARBOXYLATION; DERIVATIVES; ALDEHYDES; SARCOSINE
Research-Areas	Chemistry
Web-of-Science-Categories	Chemistry, Organic
ResearcherID-Numbers	Moshkin, Vladimir/E-6623-2017
Funding-Acknowledgement	Russian Science Foundation {[}14-13-00388]
Funding-Text	This work was financially supported by the Russian Science Foundation (Grant 14-13-00388).
Number-of-Cited-References	41
Usage-Count-Last-180-days	3
Usage-Count-Since-2013	14
Journal-ISO	Tetrahedron Lett.
Doc-Delivery-Number	CQ3OA