Dynamic speckle-interferometer for intracellular processes analyses at high optical magnification / Baharev A. A.,Vladimirov A. P.,Malygin A. S.,Mikhailova Y. A.,Novoselova I. A.,Yakin D. I.,Druzhinin A. V. // . - 2015. - V. 9529, l. .

ISSN/EISSN:

0277-786X / нет данных

Type:

Proceedings Paper

Abstract:

At present work dynamic of biospeckles is used for studying processes occurring in cells which arranged in the one layer. The basis of many diseases is changes in the structural and functional properties of the molecular cells components as caused by the influence of external factors and internal functional disorders. Purpose of work is approbation of speckle-interferometer designed for the analysis of cellular metabolism in individual cells. As a parameter, characterizing the metabolic activity of cells used the value of the correlation coefficient (eta) of optical signals proportional to the radiation intensity I, recorded at two points in time t. At 320x magnification for the cell diameter of 20 microns value eta can be determined in the area size of 6 microns.

Author keywords:

Speckle; interferometry; cell; intracellular processes; cells activity; metabolism; auto-correlation function; radiation intensity; laser; cells cultures; human diseases

DOI:

10.1117/12.2184622

Web of Science ID:

ISI:000358138000034

Соавторы в МНС:

Другие поля

Поле	Значение
Editor	Ferraro, P and Grilli, S and RitschMarte, M and Stifter, D
Booktitle	OPTICAL METHODS FOR INSPECTION, CHARACTERIZATION, AND IMAGING OF BIOMATERIALS II
Series	Proceedings of SPIE
Note	Conference on Optical Methods for Inspection, Characterization, and Imaging of Biomaterials II, Munich, GERMANY, JUN 22-24, 2015
Organization	SPIE
Publisher	SPIE-INT SOC OPTICAL ENGINEERING
Address	1000 20TH ST, PO BOX 10, BELLINGHAM, WA 98227-0010 USA
Language	English
Article-Number	95291G
ISBN	978-1-62841-689-3
Research-Areas	Materials Science; Microscopy; Optics; Radiology, Nuclear Medicine \& Medical Imaging
Web-of-Science-Categories	Materials Science, Multidisciplinary; Microscopy; Optics; Radiology, Nuclear Medicine \& Medical Imaging
ResearcherID-Numbers	Druzhinin, Anatoly/K-5765-2013 Mikhailova, Yuliya/L-3153-2015
ORCID-Numbers	Druzhinin, Anatoly/0000-0001-9944-096X
Number-of-Cited-References	14
Usage-Count-Last-180-days	7
Usage-Count-Since-2013	18
Doc-Delivery-Number	BD1LN