Synthesis of new 5-aza-isosteres of guanine containing aryl and hetaryl substituents on the 1,2,4-triazole ring / Zavodskaya A.V., Bakharev V.V., Parfenov V.E., Gidaspov A.A., Slepukhin P.A., Isenov M.L., Eltsov O.S. // Tetrahedron Letters. - 2015. - V. 56, l. 9. - P. 1103-1106.

ISSN:
00404039
Type:
Article
Abstract:
The oxidative cyclization of 4-amino-substituted 6-arylidene(hetarylmethylidene)hydrazinyl-1,3,5-triazin-2-ones with lead(IV) tetraacetate proceeds via a Dimroth-type rearrangement to give 5-amino-substituted 2-aryl(hetaryl)-1,2,4-triazolo[1,5-a]-1,3,5-triazin-7-ones. IR, NMR, and X-ray studies have shown that the only products of the reactions were the [1,5-a]-isomers. © 2015 Elsevier Ltd. All rights reserved.
Author keywords:
Index keywords:
1,2,4 triazole derivative; benzylidene derivative; guanine; Article; carbon nuclear magnetic resonance; cyclization; drug synthesis; infrared spectroscopy; proton nuclear magnetic resonance; proton tr
DOI:
10.1016/j.tetlet.2015.01.151
Смотреть в Scopus:
https://www.scopus.com/inward/record.uri?eid=2-s2.0-84922568278&doi=10.1016%2fj.tetlet.2015.01.151&partnerID=40&md5=e19f2b50bbd8bf868a10bdb201e2386b
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Link https://www.scopus.com/inward/record.uri?eid=2-s2.0-84922568278&doi=10.1016%2fj.tetlet.2015.01.151&partnerID=40&md5=e19f2b50bbd8bf868a10bdb201e2386b
Affiliations Samara State Technical University, 244 Molodogvardeyskay St., Samara, Russian Federation; I.Ya. Postovskiy Institute of Organic Synthesis, 22 S. Kovalevkaya St., Ekaterinburg, Russian Federation; Ural Federal University, 19 Mira St., Ekaterinburg, Russian Federation
Chemicals/CAS guanine, 69257-39-2, 73-40-5
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Correspondence Address Parfenov, V.E.; Samara State Technical University, 244 Molodogvardeyskay St., Russian Federation
Publisher Elsevier Ltd
CODEN TELEA
Language of Original Document English
Abbreviated Source Title Tetrahedron Lett.
Source Scopus