Synthesis of water-soluble chitosan derivatives and their use for the stabilization of liposomal suspensions / Ponomarev V. S.,Kozhikhova K. V.,Shulepov I. D.,Tokareva M. I.,Ivantsova M. N.,Mironov M. A. // RUSSIAN CHEMICAL BULLETIN. - 2014. - V. 63, l. 7. - P. 1619-1623.

ISSN/EISSN:

1066-5285 / 1573-9171

Type:

Article

Abstract:

A method was developed for chitosan modification using the multicomponent Ugi reaction. The obtained products are highly soluble in water in a wide range of pH 2-11. They were used for the stabilization of liposomal suspensions based on phosphatidylcholin, which retained colloidal stability for three months upon the addition of modified chitosan in a ratio of 1 : 5.

Author keywords:

multicomponent reactions; isocyanides; chitosan; Ugi reaction; liposomes ORAL-DRUG DELIVERY; COATED LIPOSOMES; STABILITY

DOI:

нет данных

Web of Science ID:

ISI:000350878300024

Соавторы в МНС:

Другие поля

Поле	Значение
Month	JUL
Publisher	SPRINGER
Address	233 SPRING ST, NEW YORK, NY 10013 USA
Language	English
EISSN	1573-9171
Keywords-Plus	ORAL-DRUG DELIVERY; COATED LIPOSOMES; STABILITY
Research-Areas	Chemistry
Web-of-Science-Categories	Chemistry, Multidisciplinary
Author-Email	m.a.mironov@urfu.ru
ResearcherID-Numbers	Ivantsova, Maria/R-5878-2016 Kozhikhova, Ksenia/I-8859-2017
ORCID-Numbers	Ivantsova, Maria/0000-0002-2389-0523 Kozhikhova, Ksenia/0000-0001-5124-6826
Number-of-Cited-References	19
Usage-Count-Last-180-days	6
Usage-Count-Since-2013	19
Journal-ISO	Russ. Chem. Bull.
Doc-Delivery-Number	CD2BJ