Multicomponent reactions and combinatorial chemistry / Mironov M. A. // RUSSIAN JOURNAL OF GENERAL CHEMISTRY. - 2010. - V. 80, l. 12. - P. 2628-2646.

ISSN/EISSN:

1070-3632 / 1608-3350

Type:

Article

Abstract:

Multi-component reactions (MCRs) constitute a methodology to shorter syntheses of natural products or complex molecules for drug discovery. Due to the large number of accessible compounds, this type of chemistry has become very popular between scientists who are working in the area of combinatorial chemistry. Over the last decade combinatorial chemistry has evolved from the synthesis of great quantity of simple compounds to the parallel synthesis of complex molecules with a widely varied structure. MCRs are ideally suited for this trend, being free of limitations of a traditional multistep synthesis. The close connection and interference of multicomponent reactions and combinatorial chemistry are discussed in this review.

Author keywords:

ORIENTED ORGANIC-SYNTHESIS; MULTI COMPONENT REACTIONS; SOLUTION-PHASE SYNTHESIS; 3-COMPONENT REACTION; UND STICKSTOFFWASSERSTOFFSAURE; SYNTHETIC EFFICIENCY; DOMINO REACTIONS; CONDENSATION; ISONITRILE; LIBRARIES

DOI:

10.1134/S1070363210120297

Web of Science ID:

ISI:000286663300029

Соавторы в МНС:

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Другие поля

Поле	Значение
Month	DEC
Publisher	MAIK NAUKA/INTERPERIODICA/SPRINGER
Address	233 SPRING ST, NEW YORK, NY 10013-1578 USA
Language	English
EISSN	1608-3350
Keywords-Plus	ORIENTED ORGANIC-SYNTHESIS; MULTI COMPONENT REACTIONS; SOLUTION-PHASE SYNTHESIS; 3-COMPONENT REACTION; UND STICKSTOFFWASSERSTOFFSAURE; SYNTHETIC EFFICIENCY; DOMINO REACTIONS; CONDENSATION; ISONITRILE; LIBRARIES
Research-Areas	Chemistry
Web-of-Science-Categories	Chemistry, Multidisciplinary
Author-Email	mironov@mail.ustu.ru
Number-of-Cited-References	73
Usage-Count-Since-2013	8
Journal-ISO	Russ. J. Gen. Chem.
Doc-Delivery-Number	712JP