A parallel Ugi reaction at students laboratories in the Ural and Moscow / Mironov M. A.,Babaev E. V. // RUSSIAN JOURNAL OF GENERAL CHEMISTRY. - 2010. - V. 80, l. 12. - P. 2647-2654.

ISSN/EISSN:

1070-3632 / 1608-3350

Type:

Article

Abstract:

A four-component Ugi reaction was adapted for students education. To this end, a series of almost odorless aromatic isonitriles with donor substituents was reacted with a specific carboxylic acid, phthaloyl glycine, to obtain poorly soluble (although nicely crystallized) products. The process was performed and compared in two versions by using (1) a standard centrifuge for parallel separation of precipitates and (2) parallel filtration with SynCore apparatus. It is shown for a broad series of aliphatic ketones and benzyl amines that the yields are satisfactory and the products require no further purification.

Author keywords:

нет данных

DOI:

10.1134/S1070363210120303

Web of Science ID:

ISI:000286663300030

Соавторы в МНС:

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Другие поля

Поле	Значение
Month	DEC
Publisher	MAIK NAUKA/INTERPERIODICA/SPRINGER
Address	233 SPRING ST, NEW YORK, NY 10013-1578 USA
Language	English
EISSN	1608-3350
Research-Areas	Chemistry
Web-of-Science-Categories	Chemistry, Multidisciplinary
Author-Email	mironov@mail.ustu.ru babaev@org.chem.msu.ru
ResearcherID-Numbers	Babaev, Eugene/A-8507-2011
Number-of-Cited-References	9
Usage-Count-Since-2013	3
Journal-ISO	Russ. J. Gen. Chem.
Doc-Delivery-Number	712JP