Reaction of isocyanides with thiophenols and gem-diactivated olefins: a one-pot synthesis of substituted 2-aminopyrroles / Kolontsova Anna N.,Ivantsova Maria N.,Tokareva Maria I.,Mironov Maxim A. // MOLECULAR DIVERSITY. - 2010. - V. 14, l. 3, SI. - P. 543-550.

ISSN/EISSN:

1381-1991 / нет данных

Type:

Article

Abstract:

A novel multicomponent reaction of isocyanides with thiophenols and gem-diactivated olefins has been discovered. Depending on the choice of isocyanides, substituted 2-aminopyrroles or thioimidates have been prepared. The obtained scaffolds bearing four points of diversity can directly be used in combinatorial syntheses.

Author keywords:

MCRs; Reaction design; Isocyanides; 2-Aminopyrroles; Thioimidates; Multicomponent MULTICOMPONENT REACTIONS

DOI:

10.1007/s11030-010-9233-x

Web of Science ID:

ISI:000284325800015

Соавторы в МНС:

Другие поля

Поле	Значение
Month	AUG
Publisher	SPRINGER
Address	VAN GODEWIJCKSTRAAT 30, 3311 GZ DORDRECHT, NETHERLANDS
Language	English
Keywords-Plus	MULTICOMPONENT REACTIONS
Research-Areas	Biochemistry \& Molecular Biology; Chemistry; Pharmacology \& Pharmacy
Web-of-Science-Categories	Biochemistry \& Molecular Biology; Chemistry, Applied; Chemistry, Medicinal; Chemistry, Multidisciplinary
Author-Email	mirma@mail.ustu.ru
ResearcherID-Numbers	Ivantsova, Maria/R-5878-2016
ORCID-Numbers	Ivantsova, Maria/0000-0002-2389-0523
Funding-Acknowledgement	Russian Foundation for Basic Research {[}N 07-03-96072]
Funding-Text	The authors thank Russian Foundation for Basic Research for financial support to this project (N 07-03-96072), and Prof. Dmitry N. Kozhevnikov for providing the starting reagents.
Number-of-Cited-References	13
Usage-Count-Last-180-days	2
Usage-Count-Since-2013	6
Journal-ISO	Mol. Divers.
Doc-Delivery-Number	681OK