Activities of clotting, fibrinolytic, and anticoagulant components of plasma hemostasis in patients with degenerative diseases of large joints / Antropova I.P., Yushkov B.G. // Bulletin of Experimental Biology and Medicine. - 2012. - V. 153, l. 4. - P. 505-507.

ISSN:

00074888

Type:

Article

Abstract:

Analysis of plasma hemostasis parameters was carried out in 110 patients with degenerative diseases of hip or knee joints hospitalized for initial endoprosthetics. Molecular markers of clotting and fibrinolysis and physiological anticoagulants were studied. Activities of all components of plasma hemostasis were normal in 29.4% patients. In 54.1% patients, high clotting activity was compensated for by adequate fibrinolysis activity. High thrombin formation was compensated for by high consumption of physiological anticoagulants in 10.1% patients. In 6.4% patients, high clotting activity was not paralleled by high fibrinolytic activity. © 2012 Springer Science+Business Media, Inc.

Author keywords:

Clotting; Degenerative diseases of the joints; Fibrinolysis

Index keywords:

fibrinogen; thrombin; adult; aged; anticoagulation; article; blood clotting; controlled study; enzyme linked immunosorbent assay; female; fibrinolysis; hemostasis; hip osteoarthritis; hospitalization;

DOI:

10.1007/s10517-012-1752-2

Смотреть в Scopus:

https://www.scopus.com/inward/record.uri?eid=2-s2.0-84871552534&doi=10.1007%2fs10517-012-1752-2&partnerID=40&md5=1a80cb6ebb2d488c5951b2236f573bf8

Соавторы в МНС:

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Другие поля

Поле	Значение
Link	https://www.scopus.com/inward/record.uri?eid=2-s2.0-84871552534&doi=10.1007%2fs10517-012-1752-2&partnerID=40&md5=1a80cb6ebb2d488c5951b2236f573bf8
Affiliations	V. D. Chaklin Ural Institute of Traumatology and Orthopedics, Ministry of Health Care and Social Development of the Russian Federation, Ekaterinburg, Russian Federation; Institute of Immunology and Physiology, Ural Division of the Russian Academy of Sciences, Ekaterinburg, Russian Federation
Author Keywords	Clotting; Degenerative diseases of the joints; Fibrinolysis
Chemicals/CAS	fibrinogen, 9001-32-5; thrombin, 869858-13-9, 9002-04-4; Biological Markers
References	Baeshko, A.A., Kryuchok, A.G., Yushkevich, V.A., (2000) Khirurgiya, 2, pp. 45-49; Zubairov, D.M., (2000) Molecular Bases of Blood Clotting and Clot Formation, , [in Russian], Kazan; Kuz'Min, I.I., Dubov, S.K., Kondratovskii, P.M., (2006) Thromboembolic and Hemorrhagic Complications of the Hip Joint Endoprosthetics, , [in Russian], Vladivostok; Momot, A.P., (2004) Philosophy and Algorithms of Clinical Laboratory Diagnosis of Hemostasis Disorders, , [in Russian], Barnaul; Colwell, C.W., (2009) Orthopedics, 32 (12 SUPPL.), pp. 67-73; Craven, S., Dewar, L., Yang, X., (2007) Blood Coagul. Fibrinolysis, 18 (3), pp. 219-225; Kagoma, Y.K., Crowther, M.A., Douketis, J., (2009) Thromb. Res., 123 (5), pp. 687-696; Monroe, D.M., Hoffman, M., (2006) Arterioscler. Thromb. Vasc. Biol., 26 (1), pp. 41-48; Reikeras, O., Clementsen, T., (2009) J. Thromb. Thrombolysis, 28 (4), pp. 425-428; Sokolowska, B., Piecuch, W., Walter-Croneck, A., (2002) Przegl. Lek., 59 (7), pp. 502-508; Tsai, A.W., Cushman, M., Rosamond, W.D., (2002) Am. J. Med., 113 (8), pp. 636-642; Wada, H., Kobayashi, T., Abe, Y., (2006) J. Thromb. Haemost., 4 (6), pp. 1253-1258
Correspondence Address	Antropova, I.P.; V. D. Chaklin Ural Institute of Traumatology and Orthopedics, Ministry of Health Care and Social Development of the Russian Federation, Ekaterinburg, Russian Federation; email: aip.hemolab@mail.ru
CODEN	BEXBA
PubMed ID	22977856
Language of Original Document	English
Abbreviated Source Title	Bull. Exp. Biol. Med.
Source	Scopus