Hypervalent Iodine(III) in Direct Oxidative Amination of Arenes with Heteroaromatic Amines / Manna Srimanta,Serebrennikova Polina O.,Utepova Irina A.,Antonchick Andrey P.,Chupakhin Oleg N. // ORGANIC LETTERS. - 2015. - V. 17, l. 18. - P. 4588-4591.

ISSN/EISSN:
1523-7060 / 1523-7052
Type:
Article
Abstract:
A novel, mild, and practical method of amination of simple nonfunctionalized arenes under metal free conditions has been developed. The approach allows coupling of electron-rich arenes with amino derivatives of electron-deficient heterocycles providing rapid access to scaffolds of bioactive compounds and is based on the application of the hypervalent iodine(III) reagent as an oxidant. Regioselective functionalization of C-H bonds of arenes by the formation of C-N bonds under organocatalytic conditions was demonstrated.
Author keywords:
N BOND FORMATION; C-H AMINATION; CROSS-COUPLING REACTIONS; CATALYZED INTERMOLECULAR AMINATION; AMBIENT-TEMPERATURE; COLORECTAL-CANCER; FORMING REACTIONS; PERSONAL ACCOUNT; ARYL HALIDES; COPPER
DOI:
10.1021/acs.orglett.5b02320
Web of Science ID:
ISI:000361867800049
Соавторы в МНС:
Другие поля
Поле Значение
Month SEP 18
Publisher AMER CHEMICAL SOC
Address 1155 16TH ST, NW, WASHINGTON, DC 20036 USA
Language English
EISSN 1523-7052
Keywords-Plus N BOND FORMATION; C-H AMINATION; CROSS-COUPLING REACTIONS; CATALYZED INTERMOLECULAR AMINATION; AMBIENT-TEMPERATURE; COLORECTAL-CANCER; FORMING REACTIONS; PERSONAL ACCOUNT; ARYL HALIDES; COPPER
Research-Areas Chemistry
Web-of-Science-Categories Chemistry, Organic
Author-Email andrey.antonchick@mpi-dortmund.mpg.de chupakhin@ios.uran.ru
ResearcherID-Numbers Antonchick, Andrey/P-1529-2016 Manna, Srimanta/N-6719-2015
ORCID-Numbers Antonchick, Andrey/0000-0003-0435-9443 Manna, Srimanta/0000-0002-3903-1256
Funding-Acknowledgement Max-Planck-Gesellschaft; Council on Grants of the President of the Russian Federation (Program for State Support of Leading Scientific Schools) {[}NSh-3656.2014.3]; Russian Foundation for Basic Research {[}13-03-01271]
Funding-Text We gratefully acknowledge Prof. Dr. H. Waldmann (Max-Planck-Institut fur molekulare Physiologie Dortmund) for his generous support. This work was supported by the Max-Planck-Gesellschaft, the Council on Grants of the President of the Russian Federation (Program for State Support of Leading Scientific Schools, Grant NSh-3656.2014.3) and the Russian Foundation for Basic Research (Project No. 13-03-01271).
Number-of-Cited-References 84
Usage-Count-Last-180-days 2
Usage-Count-Since-2013 46
Journal-ISO Org. Lett.
Doc-Delivery-Number CS1ZO