Heterocyclic and Open-Chain Carboranes via Transition-Metal-Free C-H Functionalization of Mono- and Diazine-N-oxides / Galliamova Lidiia A.,Varaksin Mikhail V.,Chupakhin Oleg N.,Slepukhin Pavel A.,Charushin Valery N. // ORGANOMETALLICS. - 2015. - V. 34, l. 21. - P. 5285-5290.

ISSN/EISSN:

0276-7333 / 1520-6041

Type:

Article

Abstract:

For the first time, the direct C(sp(2))-H functionalization methodology has successfully been applied to cause nucleophilic modification of mono- and diazine-N-oxides with the 1,2-closo-carborane moiety. As a result of these cross-coupling reactions uncatalyzed by transition metals, a series of novel C-modified heterocyclic and open-chain (vinyl acetylene) carboranes have been obtained. Complexes of phenanthrolinyl-substituted omicron-carborane with Cu(II) of various architectures have been synthesized.

Author keywords:

CYCLOMETALATED IRIDIUM COMPLEXES; NEUTRON-CAPTURE THERAPY; O-CARBORANE; NUCLEOPHILIC CHARACTER; BIOLOGICAL EVALUATION; RECEPTOR ANTAGONIST; CRYSTAL-STRUCTURE; ALKYL RADICALS; BORON; PHARMACOPHORES

DOI:

10.1021/acs.organomet.5b00736

Web of Science ID:

ISI:000364614400010

Соавторы в МНС:

Другие поля

Поле	Значение
Month	NOV 9
Publisher	AMER CHEMICAL SOC
Address	1155 16TH ST, NW, WASHINGTON, DC 20036 USA
Language	English
EISSN	1520-6041
Keywords-Plus	CYCLOMETALATED IRIDIUM COMPLEXES; NEUTRON-CAPTURE THERAPY; O-CARBORANE; NUCLEOPHILIC CHARACTER; BIOLOGICAL EVALUATION; RECEPTOR ANTAGONIST; CRYSTAL-STRUCTURE; ALKYL RADICALS; BORON; PHARMACOPHORES
Research-Areas	Chemistry
Web-of-Science-Categories	Chemistry, Inorganic \& Nuclear; Chemistry, Organic
Author-Email	chupakhin@ios.uran.ru
ResearcherID-Numbers	Varaksin, Mikhail/J-5007-2015
ORCID-Numbers	Varaksin, Mikhail/0000-0002-7997-3686
Funding-Acknowledgement	Ministry of Education and Science of Russian Federation {[}4.560.2014-K]; Russian Foundation for Basic Research {[}13-03-01271]; Government of the Russian Federation {[}02.A03.21.0006]
Funding-Text	This research was supported as a part of the state order of Ministry of Education and Science of Russian Federation no. 4.560.2014-K, by the Russian Foundation for the Basic Research (project no. 13-03-01271), and by the Government of the Russian Federation (Act 211, contract no. 02.A03.21.0006).
Number-of-Cited-References	71
Usage-Count-Last-180-days	1
Usage-Count-Since-2013	12
Journal-ISO	Organometallics
Doc-Delivery-Number	CV9NR