REACTIONS OF 5-(HET)ARYL-1-ETHYL-2(1H)-PYRAZINONES WITH TERMINAL ARYLACETYLENES PROMOTED BY MICROWAVE RADIATION / Verbitskiy E. V.,Cheprakova E. M.,Slepuhin P. A.,Pervova M. G.,Samorukova M. A.,Zabelina O. N.,Rusinov G. L.,Charushin V. N. // CHEMISTRY OF HETEROCYCLIC COMPOUNDS. - 2011. - V. 47, l. 6. - P. 710-718.

ISSN/EISSN:

0009-3122 / нет данных

Type:

Article

Abstract:

The reaction of 5-(het) aryl-1-ethyl-2(1H)-pyrazinones with terminal arylacetylenes, leading to a mixture of two isomeric 4-aryl- and 5-aryl-substituted 2(1H)-pyridones has been investigated. The regioselectivity of this reaction has been shown on the basis of reaction mixtures study by chromato-mass spectrometry. A crystallographic investigation of the synthesized 2(1H)-pyridones and also a forecast of their potential biological activity have been carried out.

Author keywords:

sigma(H)-adducts; arylacetylenes; 1,2-dihydropyrazines; ionic liquid; 2(1H)-pyrazinones; 2(1H)-pyridones; microwave radiation 2(1H)-PYRAZINONES

DOI:

нет данных

Web of Science ID:

ISI:000296475600007

Соавторы в МНС:

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Другие поля

Поле	Значение
Month	SEP
Publisher	SPRINGER
Address	233 SPRING ST, NEW YORK, NY 10013 USA
Language	English
Keywords-Plus	2(1H)-PYRAZINONES
Research-Areas	Chemistry
Web-of-Science-Categories	Chemistry, Organic
Author-Email	Verbitsky@ios.uran.ru
Funding-Acknowledgement	Ural Branch Russian Academy of Sciences {[}09-I-3-2004, 09-P-3-1015, 09-T-3-1022, 02.740.11.0260]; Russian Fund for Fundamental Investigations (RFFI) {[}10-03-96078-r\_ural\_a, VNSh-65261.2010.3]
Funding-Text	The work was carried out with the financial support for Programs of the Ural Branch Russian Academy of Sciences 09-I-3-2004, 09-P-3-1015, 09-T-3-1022, Goscontract No. 02.740.11.0260, and also grants from the Russian Fund for Fundamental Investigations (RFFI) 10-03-96078-r\_ural\_a and VNSh-65261.2010.3.
Number-of-Cited-References	13
Usage-Count-Last-180-days	2
Usage-Count-Since-2013	3
Journal-ISO	Chem. Heterocycl. Compds.
Doc-Delivery-Number	840XO