ipso- and tele-substitution in reactions of 3-chloro-1-ethyl-2-R-pyrazinium salts with C-nucleophiles / Slepukhin PA,Rusinov GL,Charushin VN,Kodess MI,Chupakhin ON // RUSSIAN CHEMICAL BULLETIN. - 2003. - V. 52, l. 3. - P. 689-694.

ISSN/EISSN:

1066-5285 / нет данных

Type:

Article

Abstract:

The reactions of 2,3-dichloro- and 3-cliloro-1-ethyl-2-morpholinopyrazinium tetra-fluoroborates with compounds containing the active methylene group were studied. The reactions with malonodinitrile and cyanoacetic ester afford products of ipso-substitution at position 2, while 1,3-dicarbonyl compounds produce products of tele-substitution of the Cl atom at the C(3) atom due to the attack of a nucleophile to position 6 of the pyrazine cycle.

Author keywords:

N-ethylchloropyrazinium salts; C-nucleophiles; nucleophilic substitution; NMR spectra NITROGEN NUCLEOPHILES; AMMONIA

DOI:

10.1023/A:1023919125480

Web of Science ID:

ISI:000183739500024

Соавторы в МНС:

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Другие поля

Поле	Значение
Month	MAR
Publisher	SPRINGER
Address	233 SPRING ST, NEW YORK, NY 10013 USA
Language	English
Keywords-Plus	NITROGEN NUCLEOPHILES; AMMONIA
Research-Areas	Chemistry
Web-of-Science-Categories	Chemistry, Multidisciplinary
Author-Email	charushin@prm.uran.ru
Number-of-Cited-References	13
Journal-ISO	Russ. Chem. Bull.
Doc-Delivery-Number	693VR