Novel 3-acetyl-2-methyl-polyfluorochromones in reactions with amines and esters of amino acids / Shcherbakov Konstantin V.,Bazhin Denis N.,Burgart Yanina V.,Saloutin Victor I. // CHEMISTRY OF HETEROCYCLIC COMPOUNDS. - 2015. - V. 51, l. 11-12. - P. 961-968.

ISSN/EISSN:

0009-3122 / 1573-8353

Type:

Article

Abstract:

Novel 3-acetyl-2-methyl-polyfluoro-4De-chromen-4-ones were obtained via one-pot acylation of acetylacetone with polyfluorobenzoyl chlorides. These chromones were shown to form N-substituted 3-amino-1-{[}2-hydroxy(polyfluoro)phenyl]but-2-en-1-ones in reaction with aliphatic primary amines, esters of amino acids, and aqueous ammonia via opening of the pyrone ring and deacylation.

Author keywords:

amine; chromone; acylation; deacylation; ring opening N-NUCLEOPHILES; METAL-COMPLEXES; ANTIBACTERIAL AGENTS; MEDICINAL CHEMISTRY; COPPER(II) CHELATE; PROMOTED SYNTHESIS; DERIVATIVES; BENZOPYRANS; 5,6,7,8-TETRAFLUOROCHROMONES; TRANSFORMATIONS

DOI:

10.1007/s10593-016-1805-y

Web of Science ID:

ISI:000369005200002

Соавторы в МНС:

Другие поля

Поле	Значение
Month	NOV
Publisher	SPRINGER
Address	233 SPRING ST, NEW YORK, NY 10013 USA
Language	English
EISSN	1573-8353
Keywords-Plus	N-NUCLEOPHILES; METAL-COMPLEXES; ANTIBACTERIAL AGENTS; MEDICINAL CHEMISTRY; COPPER(II) CHELATE; PROMOTED SYNTHESIS; DERIVATIVES; BENZOPYRANS; 5,6,7,8-TETRAFLUOROCHROMONES; TRANSFORMATIONS
Research-Areas	Chemistry
Web-of-Science-Categories	Chemistry, Organic
Author-Email	shcherbakov@ios.uran.ru
ResearcherID-Numbers	Bazhin, Denis/P-4667-2014 Burgart, Yanina/T-8025-2017
ORCID-Numbers	Bazhin, Denis/0000-0003-3972-6995 Burgart, Yanina/0000-0001-6061-2410
Funding-Acknowledgement	Ural Branch of the Russian Academy of Sciences {[}15-21-3-7]
Funding-Text	This work was supported by funding from the programs of the Presidium of the Ural Branch of the Russian Academy of Sciences (project 15-21-3-7).
Number-of-Cited-References	55
Usage-Count-Since-2013	4
Journal-ISO	Chem. Heterocycl. Compds.
Doc-Delivery-Number	DC1VI