C-H functionalization of triazolo{[}a]-annulated 8-azapurines / Gorbunov Evgeny B.,Rusinov Gennady L.,Ulomsky Evgeny N.,Rusinov Vladimir L.,Charushin Valery N.,Chupakhin Oleg N. // TETRAHEDRON LETTERS. - 2016. - V. 57, l. 21. - P. 2303-2305.

ISSN/EISSN:

0040-4039 / нет данных

Type:

Article

Abstract:

Direct C-H functionalization of triazolo{[}a]-annulated 8-azapurines with phenol ethers or thiophene has been performed using the oxidative nucleophilic displacement of a hydrogen on the pyrimidine ring, proceeding through the intermediacy of the corresponding sigma(H)-adducts. (C) 2016 Elsevier Ltd. All rights reserved.

Author keywords:

Fused pyrimidines; 8-Azapurines; C-H functionalization; Nucleophilic aromatic substitution of hydrogen A(1) ADENOSINE RECEPTORS; NUCLEOPHILIC-SUBSTITUTION; CARBOCYCLIC NUCLEOSIDES; ANTIVIRAL ACTIVITY; INHIBITORS; HYDROGEN; ANALOGS; ANTAGONISTS; DEAMINASE; DESIGN

DOI:

10.1016/j.tetlet.2016.04.052

Web of Science ID:

ISI:000376212300024

Соавторы в МНС:

Другие поля

Поле	Значение
Month	MAY 25
Publisher	PERGAMON-ELSEVIER SCIENCE LTD
Address	THE BOULEVARD, LANGFORD LANE, KIDLINGTON, OXFORD OX5 1GB, ENGLAND
Language	English
Keywords-Plus	A(1) ADENOSINE RECEPTORS; NUCLEOPHILIC-SUBSTITUTION; CARBOCYCLIC NUCLEOSIDES; ANTIVIRAL ACTIVITY; INHIBITORS; HYDROGEN; ANALOGS; ANTAGONISTS; DEAMINASE; DESIGN
Research-Areas	Chemistry
Web-of-Science-Categories	Chemistry, Organic
Author-Email	nitro@ios.uran.ru
Funding-Acknowledgement	Russian Foundation for Basic Research {[}14-03-31385\_youth\_a]; Russian Science Foundation {[}14-13-01301]
Funding-Text	This research study has been carried out under financial support of the Russian Foundation for Basic Research (project 14-03-31385\_youth\_a) and the Russian Science Foundation (project 14-13-01301).
Number-of-Cited-References	35
Usage-Count-Since-2013	11
Journal-ISO	Tetrahedron Lett.
Doc-Delivery-Number	DM2XV