Cyclocondensations of β-aroylacrylic acids with heterocyclic O-diamines / Kolos N., Beryozkina T., Orlov V. // Heterocycles. - 2003. - V. 60, l. 9. - P. 2115-2122.

ISSN:
03855414
Type:
Article
Abstract:
Reaction of β-aroylacrylic acids (6a-c) with 2,3-diaminopyridine (7), 5,6-diamino-1,3-dimethyluracil (8) and 2,5,6-triamino-4-oxopyrimidine (9) was studied. 1,3-Dimethyl-5,8-dihydro-1H,3H,6H-pteridine-2,4,7-trione (11c) and 2-amino-4-hydroxy-6-(2-oxo-2-phenylethyl)-5,8-dihydro-6H-pteridin-7-one (13a) were rearranged into pteridin-6-ylideneacetic acids (12c) and (14a) respectively. Reaction of α,β-dibromo-β-benzoylpropionic acid (15) with diamine (8) led to 8-benzoylpurine (17) via the step of the formation of enaminoketone (16).
Author keywords:
Index keywords:
1,3 dimethyl 5,8 dihydro 1h,3h,6h pteridine 2,4,7 trione; 2 amino 4 hydroxy 6 (2 oxo 2 phenylethyl) 5,8 dihydro 6h pteridin 7 one; 2,3 diaminopyridine; 2,5,6 triamino 4 oxopyrimidine; 5,6 diamino 1,3
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Affiliations Department of Organic Chemistry, V. N. Karazin Kharkiv Natl. Univ., Svobody sq. 4, 61077 Kharkiv, Ukraine
Chemicals/CAS 2,3 diaminopyridine, 452-58-4
References Orlov, V.D., Kolos, N.N., Yaremenko, F.G., Lavrushin, N.F., (1980) Khim. Geterotsikl. Soedin., 5, p. 697; Chebanov, V.A., Kolos, N.N., Shishkin, O.V., Shishkina, S.V., Orlov, V.D., (2003) Functional Materials, 10, p. 55; Kolos, N.N., Orlov, V.D., Chebanov, V.A., Shishkin, O.V., Kuznetsov, V.P., Kulikov, A.Yu., (1996) Chem. Heterocycl. Compd. (Engl. Tnansl.), 7, p. 978; Orlov, V.D., Kolos, N.N., Zhidkova, E.V., Papiashvili, I.Z., (1991) Khim. Geterotsikl. Soedin., 7, p. 250; Insuasty, B., Ramos, M., Quiroga, J., Sanchez, A., Nogueras, M., Hanold, N., Meier, H., (1994) J. Heterocycl. Chem., 31, p. 61; Kolos, N.N., Tischenko, A.A., Orlov, V.D., Beryozkina, T.V., Shishkin, O.V., Shishkina, S.V., (2001) Chem. Heterocycl. Compd. (Engl. Transl.), 10, p. 1407; Yudina, L.N., Preobrazhenskaya, M.N., Korolev, A.M., (2000) Chem. Heterocycl. Compd. (Engl. Transl.), 9, p. 1275; Kolos, N.N., Beryozkina, T.V., Orlov, V.D., Zhurn. Org. and Pharm. Chem., , in press; Kolos, N.N., Chebanov, V.A., Orlov, V.D., Surov, Yu.N., (2001) Chem. Heterocycl. Compd. (Engl. Transl.), 6, p. 819
Correspondence Address Orlov, V.; Department of Organic Chemistry, V. N. Karazin Kharkiv Natl. Univ., Svobody sq. 4, 61077 Kharkiv, Ukraine; email: orlov@univer.kharkov.ua
CODEN HTCYA
Language of Original Document English
Abbreviated Source Title Heterocycles
Source Scopus