Reactivity of 3-substituted pyrazole-5-diazonium salts towards 3-azolyl enamines. Synthesis of novel 3-azolylpyrazolo-{[}5,1-c]{[}1,2,4]triazines / Alexeeva Daria L.,Sadchikova Elena V.,Volkova Natalia N.,Efimov Ilya V.,Jacobs Jeroen,Van Meervelt Luc,Dehaen Wim,Bakulev Vasiliy A. // ARKIVOC. - 2016. - V. , l. 4. - P. 114-129.

ISSN/EISSN:
1551-7004 / 1551-7012
Type:
Article
Abstract:
A series of novel 3-azolylpyrazolo{[}5,1-c]{[}1,2,4]triazines was synthesized by reaction of 3-substituted pyrazole-5-diazonium salts with beta-azolyl enamines in an efficient fashion. The structures of the compounds prepared were characterized by NMR spectroscopy, mass-spectrometry, elemental and X-ray diffraction analyses. Plausible mechanisms were formulated.
Author keywords:
3-Substituted pyrazole-5-diazonium salts; enamines; pyrazolo{[}5,1-c]{[}1,2,4]triazines DIPOLAR CYCLOADDITION REACTIONS; HETEROCYCLIC DIAZONIUM SALTS; ANTITUMOR DRUG TEMOZOLOMIDE; ELECTRON-RICH; METHYLENE-COMPOUNDS; DIAZOAZOLES; IMIDAZOTETRAZINES; DERIVATIVES; ROUTES
DOI:
10.3998/ark.5550190.p009.571
Web of Science ID:
ISI:000377613000009
Соавторы в МНС:
Другие поля
Поле Значение
Publisher ARKAT USA INC
Address C/O ALAN R KATRITZKY, UNIV FLORIDA, DEPT CHEMISTRY, PO BOX 117200, GAINESVILLE, FL 32611 USA
Language English
EISSN 1551-7012
Keywords-Plus DIPOLAR CYCLOADDITION REACTIONS; HETEROCYCLIC DIAZONIUM SALTS; ANTITUMOR DRUG TEMOZOLOMIDE; ELECTRON-RICH; METHYLENE-COMPOUNDS; DIAZOAZOLES; IMIDAZOTETRAZINES; DERIVATIVES; ROUTES
Research-Areas Chemistry
Web-of-Science-Categories Chemistry, Organic
Author-Email e.v.sadchikova@urfu.ru
ResearcherID-Numbers Efimov, Ilya/H-8741-2016
ORCID-Numbers Efimov, Ilya/0000-0003-1123-987X
Funding-Acknowledgement Ministry of Education and Science of the Russian Federation {[}4.1626.2014/K]; Russian Foundation for Basic Research {[}14-03-01033]; Hercules Foundation {[}AKUL/09/0035]
Funding-Text The Russian authors thank the Ministry of Education and Science of the Russian Federation (State task 4.1626.2014/K) and Russian Foundation for Basic Research (grant No 14-03-01033) for financial support. The authors from Belgium thank the Hercules Foundation for supporting the purchase of equipment through the project AKUL/09/0035, Molybdenum high-energy X-ray source for in-situ diffraction studies of advanced materials and single crystals.
Number-of-Cited-References 39
Usage-Count-Last-180-days 3
Usage-Count-Since-2013 7
Journal-ISO Arkivoc
Doc-Delivery-Number DO2MC