Sex Differences in Behavioral Reactions and the Character of Audiogenic Seizures in Krushinsky-Molodkina Rat Strain / Krivopalov S.A., Yushkov B.G. // Zhurnal vyssheĭ nervnoĭ deiatelnosti imeni I P Pavlova. - 2015. - V. 65, l. 6. - P. 756-765.

ISSN:

00444677

Type:

Article

Abstract:

In the "open field" test it was found that locomotor activity in Krushinsky-Molodkina rat strain (KM) is higher than in nonlinear animals. At the same time, both groups of animals had the same sex differences: a locomotor activity of females was higher than males. Sex differences in exploratory activities are not inherent for KM rats, while the female outbred animals are significantly higher than males in their level of such activities. The greatest differences in behavior between KM rats and outbred animals were found in anxiety level, which is much higher in the first case. Furthermore just KM rats are characterized by clear sex differences--the males demonstrate more anxious and fearful respond to unfamiliar surroundings than females. Male and female KM rats differ not only in behavior but also in the character of epileptiform seizures induced by loud sound: wild running, tonic-clonic and clonic convulsions occur faster in females and the resumption of breathing-in males. The interconnection between parameters of seizure and behavior was found for KM rats. This phenomenon is most clearly manifested in males and combine large group of indicators.

Author keywords:

Index keywords:

animal; anxiety; female; male; motor activity; pathophysiology; physiology; rat; reflex epilepsy; sexual development; Animals; Anxiety; Epilepsy, Reflex; Female; Male; Motor Activity; Rats; Sex Charac

DOI:

нет данных

Смотреть в Scopus:

https://www.scopus.com/inward/record.uri?eid=2-s2.0-84960991849&partnerID=40&md5=7adbb06ed111c16dcf38a0069ad36178

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Другие поля

Поле	Значение
Link	https://www.scopus.com/inward/record.uri?eid=2-s2.0-84960991849&partnerID=40&md5=7adbb06ed111c16dcf38a0069ad36178
PubMed ID	26841663
Language of Original Document	Russian
Abbreviated Source Title	Zh Vyssh Nerv Deiat Im I P Pavlova
Source	Scopus